Product Name :
Zosuquidar trihydrochloride
Description:
Zosuquidar, also known as LY-335979, is a potent P-glycoprotein (P-gp) inhibitor, which binds with high affinity to P-glycoprotein and inhibits P-glycoprotein-mediated multidrug resistance (MDR). P-glycoprotein, encoded by the MDR-1 gene, is a member of the ATP-binding cassette superfamily of transmembrane transporters and prevents the intracellular accumulation of many natural product-derived cytotoxic agents.
CAS:
167465-36-3
Molecular Weight:
636.99
Formula:
C32H34Cl3F2N3O2
Chemical Name:
(2R)-1-4-[(2R,4S)-3,3-difluorotetracyclo[10.4.0.0²,⁴.0⁵,¹⁰]hexadeca-1(16),5,7,9,12,14-hexaen-11-yl]piperazin-1-yl-3-(quinolin-5-yloxy)propan-2-ol trihydrochloride
Smiles :
Cl.Cl.Cl.O[C@H](CN1CCN(CC1)C1C2=CC=CC=C2[C@H]2[C@@H](C3=CC=CC=C31)C2(F)F)COC1=CC=CC2=NC=CC=C21
InChiKey:
ZPFVQKPWGDRLHL-ZLYBXYBFSA-N
InChi :
InChI=1S/C32H31F2N3O2.3ClH/c33-32(34)29-22-7-1-3-9-24(22)31(25-10-4-2-8-23(25)30(29)32)37-17-15-36(16-18-37)19-21(38)20-39-28-13-5-12-27-26(28)11-6-14-35-27;;;/h1-14,21,29-31,38H,15-20H2;3*1H/t21-,29-,30+,31?;;;/m1.Ripasudil Biological Activity ../s1
Purity:
≥98% (or refer to the Certificate of Analysis)
Shipping Condition:
Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition :
Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.Fenoprofen Purity & Documentation
Shelf Life:
≥360 days if stored properly.
Stock Solution Storage:
0 – 4 oC for 1 month or refer to the Certificate of Analysis.
Additional information:
Zosuquidar, also known as LY-335979, is a potent P-glycoprotein (P-gp) inhibitor, which binds with high affinity to P-glycoprotein and inhibits P-glycoprotein-mediated multidrug resistance (MDR). P-glycoprotein, encoded by the MDR-1 gene, is a member of the ATP-binding cassette superfamily of transmembrane transporters and prevents the intracellular accumulation of many natural product-derived cytotoxic agents.|Product information|CAS Number: 167465-36-3|Molecular Weight: 636.99|Formula: C32H34Cl3F2N3O2|Chemical Name: (2R)-1-4-[(2R,4S)-3,3-difluorotetracyclo[10.PMID:33021357 4.0.0²,⁴.0⁵,¹⁰]hexadeca-1(16),5,7,9,12,14-hexaen-11-yl]piperazin-1-yl-3-(quinolin-5-yloxy)propan-2-ol trihydrochloride|Smiles: Cl.Cl.Cl.O[C@H](CN1CCN(CC1)C1C2=CC=CC=C2[C@H]2[C@@H](C3=CC=CC=C31)C2(F)F)COC1=CC=CC2=NC=CC=C21|InChiKey: ZPFVQKPWGDRLHL-ZLYBXYBFSA-N|InChi: InChI=1S/C32H31F2N3O2.3ClH/c33-32(34)29-22-7-1-3-9-24(22)31(25-10-4-2-8-23(25)30(29)32)37-17-15-36(16-18-37)19-21(38)20-39-28-13-5-12-27-26(28)11-6-14-35-27;;;/h1-14,21,29-31,38H,15-20H2;3*1H/t21-,29-,30+,31?;;;/m1…/s1|Technical Data|Appearance: Solid Power|Purity: ≥98% (or refer to the Certificate of Analysis)|Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis|Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.|Shelf Life: ≥360 days if stored properly.|Stock Solution Storage: 0 – 4 oC for 1 month or refer to the Certificate of Analysis.|Drug Formulation: To be determined|HS Tariff Code: 382200|Products are for research use only. Not for human use.|
