Product Name :
COL4A3 Human
Description :
Human α3 chain of collagen IV; identical with the antigen called “glomerular basal membrane antigen” (GBM). Recombinant antigen for solid (ELISA) and fluid phase diagnostic assays. Calculated Molecular weight: 53kDa. Calculated isoelectric point: pH 8.9.cDNA coding for a minicollagen version of the human collagen IV α3 chain fused to a hexa-histidine purification tag. The term minicollagen designates the removal of most of the epitope-less triplehelical collagenous region (situated between the N-terminal 7S domain and the C-terminal noncollagenous NC1 domain), which is a requirement for recombinant production of this antigen.
Background :
Biological activity:
Protein number :
Q01955
Synonyms:
Collagen alpha-3(IV) chain, Goodpasture antigen, COL4A3, Glomerular Basal Membrane, GBM.
Amino acid sequence :
Purity :
Greater than 95.0% as determined by SDS-PAGE.
Source :
Sf9 insect cells.
Stablity :
Recommendations for storage buffer: neutral to slightly alkaline pH and 4M urea as dissociating agent.Storage temperature: -70°C to -80°C.Please prevent freeze-thaw cycles.
MedChemExpress (MCE) recombinant proteins include: cytokines, enzymes, growth factors, hormones, receptors, transcription factors, antibody fragments, etc. They are often essential for supporting cell growth, stimulating cell signaling pathways, triggering or inhibiting cell differentiation; and are useful tools for elucidating protein structure and function, understanding disease onset and progression, and validating pharmaceutical targets. At MedChemExpress (MCE), we strive to provide products with only the highest quality. Protein identity, purity and biological activity are assured by our robust quality control and assurance procedures.
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